Genetic Models at MCW

If interested in obtaining any of these strains, please contact mcwcustomrats@mcw.edu .   

  

Genetic Models Available

Gene Symbol Gene No. of Models Background Strain Strain Symbol Aliases Method Availability Origination Phenotype Data Publications Ask about this Model!
Prune1 prune exopolyphosphatase 1 2
Adora1 adenosine A1 receptor 2
Spta1 spectrin, alpha, erythrocytic 1 1 F344/NCrl F344-Spta1Tn(sb-T2/Bart3)2.315Mcwi RRRC:00439 Sleeping Beauty Cryopreserved Sperm (as of 2017-01-26) PhysGen Publications
Ghsr growth hormone secretagogue receptor 2
Has2 hyaluronan synthase 2 1 BN/NHsdMcwi BN-Has2m1Mcwi ENU Unknown PGA
Tlr4 toll-like receptor 4 1 FHH/EurMcwi FHH-Tlr4m1Mcwi RRRC:00411 ENU Cryopreserved Sperm (as of 2017-01-26) PhysGen Phenominer Link
Rapgef4 Rap guanine nucleotide exchange factor 4 1 F344/NCrl F344-Rapgef4Tn(sb-T2/Bart3)2.314Mcwi RRRC:00479 Sleeping Beauty Cryopreserved Sperm (as of 2017-01-26) PhysGen Publications
Tph1 tryptophan hydroxylase 1 2
Grk1 G protein-coupled receptor kinase 1 1 F344/NCrl F344-Grk1Tn(sb-T2/Bart3)2.234Mcwi RRRC: 0388 Sleeping Beauty Cryopreserved Sperm (as of 2017-01-26) PhysGen Publications
Aldh2 aldehyde dehydrogenase 2 family (mitochondrial) 1 SS/JrHsdMcwi SS-Aldh2em2Mcwi ZFN Cryopreserved Sperm (as of 2017-01-26) PhysGen Knockouts Phenominer Link Publications
Cd55 CD55 molecule, decay accelerating factor for complement 1 Crl:SD SD-Cd55em4Mcwi CRISPR/Cas9 Live Animals (as of 2017-08-02) MCW Gene Editing Rat Resource Center
Klhl13 kelch-like family member 13 1 F344/NCrl F344-Klhl13Tn(sb-T2/Bart3)2.176Mcwi Sleeping Beauty Unknown PGA Publications
Ndufc2 NADH:ubiquinone oxidoreductase subunit C2 2
Syndig1 synapse differentiation inducing 1 1 F344/NCrl F344-Syndig1Tn(sb-T2/Bart3)2.171Mcwi F344-RGD1310753Tn(sb-T2/Bart3)2.171Mcwi ;
RRRC:00342
Sleeping Beauty Cryopreserved Sperm (as of 2017-01-26) PhysGen Publications
Nr4a1 nuclear receptor subfamily 4, group A, member 1 1 FHH/EurMcwi FHH-Nr4a1m1Mcwi ENU Cryopreserved Sperm (as of 2017-01-26) PhysGen Phenominer Link
Adora2b adenosine A2B receptor 2
Agtr1a angiotensin II receptor, type 1a 2
Nectin1 nectin cell adhesion molecule 1 1 F344/NCrl F344-Nectin1Tn(sb-T2/Bart3)2.284Mcwi F344-Pvrl1Tn(sb-T2/Bart3)2.284Mcwi ;
RRRC:00378
Sleeping Beauty Cryopreserved Sperm (as of 2017-01-26) PhysGen Publications
Cadm2 cell adhesion molecule 2 1 F344/NCrl F344-Cadm2Tn(sb-T2/Bart3)2.180Mcwi F344-Igsf4dTn(sb-T2/Bart3)2.180Mcwi ;
F344-Igsf4d_predictedTn(sb-T2/Bart3)2.180Mcwi ;
F344-Igsf4d_predictedTn(sb-T2/Bart3)2.180Mcwi
Sleeping Beauty Unknown PGA Publications
Proc protein C, inactivator of coagulation factors Va and VIIIa 1 FHH/EurMcwi FHH-Procm1Mcwi RRRC:00410 ENU Cryopreserved Sperm (as of 2017-01-26) PhysGen Phenominer Link
Comt catechol-O-methyltransferase 1 SS/JrHsdMcwi SS-Comtem1Mcwi ZFN Cryopreserved Sperm (as of 2017-01-26) PhysGen Knockouts Publications
Ube2q2 ubiquitin conjugating enzyme E2 Q2 1 SS/JrHsdMcwi SS-Ube2q2em3Mcwi ZFN Cryopreserved Sperm (as of 2017-01-26) PhysGen Knockouts Phenominer Link Publications
Shc1 SHC adaptor protein 1 4
Kcnj11 potassium voltage-gated channel subfamily J member 11 2
Fam227a family with sequence similarity 227, member A 1 F344/NCrl F344-Fam227aTn(sb-T2/Bart3)2.333Mcwi F344-LOC685444Tn(sb-T2/Bart3)2.333Mcwi ;
RRRC:0484 ;
F344-LOC685444Tn(sb-T2/Bart3)2.333Mcwi
Sleeping Beauty Cryopreserved Sperm (as of 2017-01-26) PhysGen Publications
Nppb natriuretic peptide B 2
Asic3 acid sensing ion channel subunit 3 1 WKY/NCrl WKY-Asic3em6Mcwi CRISPR/Cas9 Cryorecovery (as of 2017-08-14) MCW Gene Editing Rat Resource Center
Trpc6 transient receptor potential cation channel, subfamily C, member 6 3
Myo9a myosin IXA 1 F344/NCrl F344-Myo9aTn(sb-T2/Bart3)2.186Mcwi RRRC:00385 Sleeping Beauty Cryopreserved Sperm (as of 2017-01-26) PhysGen Phenominer Link Publications
Ccdc85a coiled-coil domain containing 85A 1 F344/NCrl F344-Ccdc85aTn(sb-T2/Bart3)2.248Mcwi RRRC:0356 Sleeping Beauty Cryopreserved Sperm (as of 2017-01-26) PhysGen Publications
Nsun4 NOP2/Sun RNA methyltransferase family member 4 1 F344/NCrl F344-Nsun4Tn(sb-T2/Bart3)2.286Mcwi RRRC:00435 Sleeping Beauty Cryopreserved Sperm (as of 2017-01-26) PhysGen Publications
Itga9 integrin subunit alpha 9 1 SS/JrHsdMcwi SS-Itga9em1Mcwi ZFN Cryopreserved Sperm (as of 2017-01-26) PhysGen Knockouts Phenominer Link Publications
Lss lanosterol synthase 1 SS/JrHsdMcwi SS-Lssem2Mcwi ZFN Cryopreserved Sperm (as of 2017-01-26) PhysGen Knockouts Publications
Igh-6 immunoglobulin heavy chain 6 2
Gramd1b GRAM domain containing 1B 1 F344/NCrl F344-Gramd1bTn(sb-T2/Bart3)2.287Mcwi RRRC: 0389 Sleeping Beauty Cryopreserved Sperm (as of 2017-01-26) PhysGen Publications
Robo1 roundabout guidance receptor 1 1 F344/NCrl F344-Robo1Tn(sb-T2/Bart3)2.327Mcwi RRRC:00451 Sleeping Beauty Cryopreserved Sperm (as of 2017-01-26) PhysGen Publications
Ren renin 1 SS/JrHsdMcwi SS-Renem1Mcwi ZFN Live Animals; Cryopreserved Sperm (as of 2017-01-26) PhysGen Knockouts Phenominer Link Publications
Kcnj16 potassium voltage-gated channel subfamily J member 16 1 SS/JrHsdMcwi SS-Kcnj16em1Mcwi ZFN Live Animals; Cryopreserved Sperm (as of 2017-01-26) PhysGen Knockouts Publications
Ldlr low density lipoprotein receptor 2
Mrpl28 mitochondrial ribosomal protein L28 1 LEW/NCrl LEW-Mrpl28em1Mcwi CRISPR/Cas9 Cryopreserved Sperm (as of 2017-01-26) MCW Gene Editing Rat Resource Center
Alms1 ALMS1, centrosome and basal body associated protein 1 SS/JrHsdMcwi SS-Alms1em1Mcwi ZFN Cryopreserved Sperm (as of 2017-01-26) PhysGen Knockouts Phenominer Link Publications
Kcnab1 potassium voltage-gated channel subfamily A member regulatory beta subunit 1 1 F344/NCrl F344-Kcnab1Tn(sb-T2/Bart3)2.300Mcwi RRRC:0471 Sleeping Beauty Cryopreserved Sperm (as of 2017-01-26) PhysGen Publications
Cd247 Cd247 molecule 2
Cyss cystatin S 1 F344/NCrl F344-CyssTn(sb-T2/Bart3)2.173Mcwi Sleeping Beauty Unknown PGA Publications
Cyba cytochrome b-245 alpha chain 1 SS/JrHsdMcwi SS-Cybaem1Mcwi ZFN Live Animals; Cryopreserved Sperm (as of 2017-01-26) PhysGen Knockouts Phenominer Link Publications