Genetic Models at MCW

If interested in obtaining any of these strains, please contact mcwcustomrats@mcw.edu .   

  

Genetic Models Available

Gene Symbol Gene No. of Models Background Strain Strain Symbol Aliases Method Availability Origination Phenotype Data Publications Ask about this Model!
Plod1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 1 SS/JrHsdMcwi SS-Plod1em1Mcwi ZFN Cryorecovery (as of 2017-01-26) PhysGen Knockouts Phenominer Link Publications
Spata13 spermatogenesis associated 13 1 F344/NCrl F344-Spata13Tn(sb-T2/Bart3)2.267Mcwi RRRC:00373 Sleeping Beauty Cryopreserved Sperm (as of 2017-01-26) PhysGen Publications
Abat 4-aminobutyrate aminotransferase 1 F344/NCrl F344-AbatTn(sb-T2/Bart3)2.163Mcwi RRRC:0381 Sleeping Beauty Cryopreserved Sperm (as of 2016-11-11) PGA , Transposagen, Rat Resource & Research Center Phenominer Link Publications
Ada adenosine deaminase 1 F344/NCrl F344-AdaTn(sb-T2/Bart3)2.237Mcwi RRRC:0426 Sleeping Beauty Cryopreserved Sperm (as of 2017-01-13) PhysGen Publications
Trdn triadin 1 F344/NCrl F344-TrdnTn(sb-T2/Bart3)2.238Mcwi RRRC:00368 Sleeping Beauty Cryopreserved Sperm (as of 2017-01-26) PhysGen Publications
Syne1 spectrin repeat containing nuclear envelope protein 1 1 F344/NCrl F344-Syne1Tn(sb-T2/Bart3)2.68Mcwi RRRC:00325 Sleeping Beauty Cryopreserved Sperm (as of 2017-01-26) PhysGen Publications
Proc protein C, inactivator of coagulation factors Va and VIIIa 1 FHH/EurMcwi FHH-Procm1Mcwi RRRC:00410 ENU Cryopreserved Sperm (as of 2017-01-26) PhysGen Phenominer Link
Immp1l inner mitochondrial membrane peptidase subunit 1 1 F344/NCrl F344-Immp1lTn(sb-T2/Bart3)2.246Mcwi RRRC: 0355 Sleeping Beauty Cryopreserved Sperm (as of 2017-01-26) PhysGen Publications
Comt catechol-O-methyltransferase 1 SS/JrHsdMcwi SS-Comtem1Mcwi ZFN Cryopreserved Sperm (as of 2017-01-26) PhysGen Knockouts Publications
Cst3 cystatin C 3
Myo9a myosin IXA 1 F344/NCrl F344-Myo9aTn(sb-T2/Bart3)2.186Mcwi RRRC:00385 Sleeping Beauty Cryopreserved Sperm (as of 2017-01-26) PhysGen Phenominer Link Publications
Trpc3 transient receptor potential cation channel, subfamily C, member 3 2
Pon3 paraoxonase 3 1 SS-Pon3em1Mcwi CRISPR/Cas9 Cryorecovery (as of 2017-07-18) MCW Gene Editing Rat Resource Center
Sorcs1 sortilin-related VPS10 domain containing receptor 1 2
Sugp1 SURP and G patch domain containing 1 1 F344/NCrl F344-Sf4Tn(sb-T2/Bart3)2.264Mcwi RRRC:00371 Sleeping Beauty Cryopreserved Sperm (as of 2017-01-26) PhysGen Publications
Adora2b adenosine A2B receptor 2
Adra2a adrenoceptor alpha 2A 1 SS/JrHsdMcwi SS-Adra2aem1Mcwi ZFN Cryopreserved Sperm (as of 2017-01-26) PhysGen Knockouts Phenominer Link Publications
Rbm20 RNA binding motif protein 20 3
Lzic leucine zipper and CTNNBIP1 domain containing 1 F344/NCrl F344-LzicTn(sb-T2/Bart3)2.309Mcwi RRRC:00434 Sleeping Beauty Cryopreserved Sperm (as of 2017-01-26) PhysGen Publications
Pebp4 phosphatidylethanolamine binding protein 4 1 F344/NCrl F344-Pebp4Tn(sb-T2/Bart3)2.299Mcwi RRRC: 0455 Sleeping Beauty Cryopreserved Sperm (as of 2017-01-26) PhysGen Publications
Adora2a adenosine A2a receptor 2
Kcnab1 potassium voltage-gated channel subfamily A member regulatory beta subunit 1 1 F344/NCrl F344-Kcnab1Tn(sb-T2/Bart3)2.300Mcwi RRRC:0471 Sleeping Beauty Cryopreserved Sperm (as of 2017-01-26) PhysGen Publications
Cpt2 carnitine palmitoyltransferase 2 1 SS/JrHsdMcwi SS-Cpt2m1Mcwi RRRC:00416 ENU Cryopreserved Sperm (as of 2017-01-26) PhysGen Phenominer Link
Ace angiotensin I converting enzyme 2
Mb myoglobin 1 WKY/NCrl WKY-Mbem6Mcwi CRISPR/Cas9 Cryorecovery (as of 2017-07-18) MCW Gene Editing Rat Resource Center
Dlg1 discs large MAGUK scaffold protein 1 1 F344/NCrl F344-Dlg1Tn(sb-T2/Bart3)2.133Mcwi Sleeping Beauty Unknown PGA Publications
Lrrc4c leucine rich repeat containing 4C 1 F344/NCrl F344-Lrrc4cTn(sb-T2/Bart3)2.254Mcwi RRRC:00359 Sleeping Beauty Cryopreserved Sperm (as of 2017-01-26) PhysGen Publications
Kif16b kinesin family member 16B 1 F344/NCrl F344-Kif16bTn(sb-T2/Bart3)2.200Mcwi RRRC:0346 Sleeping Beauty Cryopreserved Sperm (as of 2017-01-26) PhysGen Publications
Mmp2 matrix metallopeptidase 2 1 SS/JrHsdMcwi SS-Mmp2em2Mcwi ZFN Unknown (as of 2017-07-18) PhysGen Knockouts Phenominer Link Publications
Agtrap angiotensin II receptor-associated protein 2
Pde4d phosphodiesterase 4D 1 F344/NCrl F344-Pde4dTn(sb-T2/Bart3)2.285Mcwi RRRC:00436 Sleeping Beauty Cryopreserved Sperm (as of 2017-01-26) PhysGen Publications
Diaph3 diaphanous-related formin 3 1 F344/NCrl F344-Diaph3Tn(sb-T2/Bart3)2.318Mcwi RRRC:0446 Sleeping Beauty Cryopreserved Sperm (as of 2017-01-26) PhysGen Publications
Mstn myostatin 2
Cubn cubilin 1 SS/JrHsdMcwi SS-Cubnem1Mcwi ZFN Cryopreserved Sperm (as of 2017-01-26) PhysGen Knockouts Publications
Brinp3 BMP/retinoic acid inducible neural specific 3 1 F344/NCrl F344-Brinp3Tn(sb-T2/Bart3)2.189Mcwi RRRC:0425 ;
F344-Fam5cTn(sb-T2/Bart3)2.189Mcwi
Sleeping Beauty Cryopreserved Sperm (as of 2017-01-26) PhysGen Phenominer Link Publications
Fyn FYN proto-oncogene, Src family tyrosine kinase 1 SS/JrHsdMcwi SS-Fynem6Mcwi ZFN Cryopreserved Sperm (as of 2017-01-26) PhysGen Knockouts Publications
Inpp4b inositol polyphosphate-4-phosphatase type II B 1 F344/NCrl F344-Inpp4bTn(sb-T2/Bart3)2.143Mcwi RRRC:0379 Sleeping Beauty Cryopreserved Sperm (as of 2017-01-26) PhysGen Phenominer Link Publications
Btg2 BTG anti-proliferation factor 2 4
Prex1 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 1 SS/JrHsdMcwi SS-Prex1em2Mcwi ZFN Cryopreserved Sperm (as of 2017-01-26) PhysGen Knockouts Publications
Nat8 N-acetyltransferase 8 1 SS/JrHsdMcwi SS-Nat8em4Mcwi ZFN Cryopreserved Sperm (as of 2017-01-26) PhysGen Knockouts Publications
Chsy1 chondroitin sulfate synthase 1 1 F344/NCrl F344-Chsy1Tn(sb-T2/Bart3)2.165Mcwi F344-Chsy1_predictedTn(sb-T2/Bart3)2.165Mcwi ;
F344-Chsy1_predictedTn(sb-T2/Bart3)2.165Mcwi ;
RRRC:0337
Sleeping Beauty Cryopreserved Sperm (as of 2017-01-26) PhysGen Publications
Kcnip4 potassium voltage-gated channel interacting protein 4 1 F344/NCrl F344-Kcnip4Tn(sb-T2/Bart3)2.225Mcwi RRRC:0348 Sleeping Beauty Cryopreserved Sperm (as of 2017-01-26) PhysGen Publications
Lepr leptin receptor 1 SS/JrHsdMcwi SS-Leprem2Mcwi ZFN Cryopreserved Sperm (as of 2017-01-26) PhysGen Knockouts Publications
Gla galactosidase, alpha 1 DA/MolTac DA-Glaem2Mcwi CRISPR/Cas9 Live Animals; Cryorecovery (as of 2017-07-18) MCW Gene Editing Rat Resource Center
Sorcs2 sortilin-related VPS10 domain containing receptor 2 4